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The rundown on coronavirus

You don't have to be a scientist to do science! Download and play Foldit and you can help researchers discover new antiviral drugs that might stop coronavirus! The most promising solutions will be manufactured and tested at the University of Washington Institute for Protein Design in Seattle.

Foldit is run by academic research scientists. It is free to play and not-for-profit. To get started, download Foldit and create a username!

We recommend that new players start with the Foldit Intro Puzzles.
After some practice, move on to the Science Puzzles and try out the Beginner: Coronavirus puzzle.
We also have an advanced puzzle NEW advanced puzzle where you can try to design an antiviral protein from scratch!

To meet other players, check out the Foldit Discord channels.

Note: Foldit is an interactive computer game and not a distributed computing project. If you would like to donate idle CPU cycles to science, please check out the Rosetta@Home project on BOINC.

(Wed, 03/04/2020 - 05:46  |  9 comments)

Join our Discord!

We've recently put up a Discord server. Join here!:

(Tue, 03/03/2020 - 23:02  |  3 comments)

Foldit Lab Report #6: Coronavirus puzzle

Check out Foldit Lab Report #6 on YouTube now!

We've got a bunch of new puzzles this month — and some exciting tools coming soon!

NEWS
• Looking at electron density in Foldit is about to get a whooole lot easier (0:31)
• With the new BUNS tool, your solutions should be better behaved in the lab (2:18)

PUZZLE UPDATES
• More poly-proline helix design (3:50)
• CRISPR/Cas transposase (4:02)
• Aflatoxin prediction (4:28)
• Coronavirus spike-binder design (5:20)
• Return of sketchbooks — this time symmetric (6:10)

You can still fill out the username sharing form to let us know you're okay with public recognition!

(Sun, 03/01/2020 - 17:09  |  5 comments)

New coronavirus puzzle!

The Baker Lab is trying to design proteins that could be used as antiviral agents against the 2019 coronavirus! Check out Puzzle 1805b and design a protein that can bind the coronavirus spike protein!

(Fri, 02/28/2020 - 20:37  |  2 comments)

Foldit Lab Report #5: New software dev

Check out Foldit Lab Report #5 on YouTube now!

NEWS
- This month we welcome Henry! (aka milkshake)
- Check the Foldit blog for an update on DeepMind's AlphaFold

PUZZLE UPDATES
- New poly-proline helix tools are on the way
- Introducing a CRISPR puzzle
- Ever more symmetric designs
- Can you make the next top TIM?

DESIGN OF THE MONTH
- silent gene created another great symmetric design

(Sat, 02/01/2020 - 20:31  |  5 comments)
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons