puzzle picture
864: De-novo Freestyle 36: Low Power
Status: Closed

Summary

Name: 864: De-novo Freestyle 36: Low Power
Status: Closed
Created: 03/25/2014
Points: 100
Expired: 04/01/2014 - 23:00
Difficulty: Intermediate
Description: In this de-novo freestyle puzzle, the "High Wiggle Power" option has been disabled. After this puzzle expires, the puzzle will be reposted for a brief period with the High Wiggle Power option enabled, and you will be able to load in solutions from this puzzle. The results from these puzzles will help us determine how useful the wiggle power options may be for structure prediction in Foldit. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.
Categories: Overall, Prediction

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Comments

bkoep's picture
User offline. Last seen 3 hours 33 min ago. Offline
Joined: 11/15/2012
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

________________

If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

wisky's picture
User offline. Last seen 6 weeks 8 hours ago. Offline
Joined: 07/13/2011
...

*screams*

YOU BETTER NOT TAKE AWAY MY HIGH WIGGLE POWER!!!!!! AHHHHHHHHH!!!!!!!!!!

In all seriousness, this is probably a good thing. Glad you're testing this out before CASP :)

alcor29's picture
User offline. Last seen 12 hours 7 min ago. Offline
Joined: 11/16/2012
High Power

I sure hope it turns out High is indispensable; and you aren't just going to roll the functions into another power. While it might make sense, it would take away the fun of anticipating going to high and shooting up in the score, and watching the green rank ups scroll by. We gotta a little fun, folks.

Joined: 04/19/2009
Whether intentional or not...

Low is not acting like Low in this puzzle. I was able to stabilize a .2 start way easier than any other denovo you have posted since NC began. It's acting more like Auto usually does.

frood66's picture
User offline. Last seen 10 hours 5 min ago. Offline
Joined: 09/20/2011
Groups: Marvin's bunch
Who put the super glue in

Who put the super glue in this one?

Joined: 06/06/2013
Groups: Gargleblasters
high wiggle power

I usually try a rough wiggle to get a sense of what the puzzle should be, reset and manually try to set a neat structure. That said, I'm on old equipment, so High Wiggle Power sometimes is the only way I can get a puzzle to move along once I have a general structure set.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons