puzzle picture
737: Unsolved Salmonella Bacteriophage: Freestyle Hand-folding Round
Status: Closed

Summary

Name: 737: Unsolved Salmonella Bacteriophage: Freestyle Hand-folding Round
Status: Closed
Created: 06/25/2013
Points: 100
Expired: 07/04/2013 - 01:00
Difficulty: Intermediate
Description: This is the first of many puzzles for this unsolved protein. We are giving you an extended chain; sadly this protein has no homologs or templates we can use. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, it will be re-posted and LUA scripts and sharing will be allowed. You'll also be able to load in your solutions from this puzzle. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.
Categories: Hand-Folding, Overall, Prediction

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Comments

beta_helix's picture
User offline. Last seen 1 day 16 hours ago. Offline
Joined: 05/09/2008
Groups: None
More details:

Here are the secondary structure predictions predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Leucines at residues 39 and 100 are highly predicted to be part of a helix. However, the Leucines at residues 39 and 82 are predicted to be part of a sheet!

marie_s's picture
User offline. Last seen 1 year 23 weeks ago. Offline
Joined: 05/18/2008
Groups: None
the image
beta_helix's picture
User offline. Last seen 1 day 16 hours ago. Offline
Joined: 05/09/2008
Groups: None
thank you Marie

Hopefully I've fixed this and the secondary structure predictions now show up again!

Joined: 05/26/2008
Groups: Hold My Beer
It's good ! I am curious do

It's good ! I am curious do you have predictions of where the "correct" structure should score ?

beta_helix's picture
User offline. Last seen 1 day 16 hours ago. Offline
Joined: 05/09/2008
Groups: None
That is a great question...

but sadly your guess is as good as ours on this one.

The one thing that we can be sure of is that your solutions for Round 2 will score higher than this hand-folding round!

Joined: 05/26/2008
Groups: Hold My Beer
Thank you, just wondering if

Thank you,

just wondering if it's worth it to pursue it further, running out of steam on it.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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