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GTPase Ras
Status: Closed

Summary

Name: GTPase Ras
Status: Closed
Created: 11/26/2011
Points: 100
Difficulty: Advanced
Description: The conformational change occurring in the small GTPase Ras is extremely important for the molecular basis of many cancers. The GTP-bound conformation of this protein should be in an ON state, signaling cell growth. Can you help it find this native fold?
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Microsoft, Adobe, RosettaCommons