Sci Chat Roundup (Developer Edition)
We had a number of development style questions during our last open call for science chat questions, and as such, weren’t able to prioritize those during our last busy chat. We still wanted to get these answered for everyone, so here they are.
Will a parallel programming language, such as CUDA or OpenCL, ever be used to optimize processing speed in Foldit? Source question
Most of the heavy-weight processing is done inside of Rosetta, so if and when it is added, we can consider it. Aside from the technical problems, this also introduces potential social problems. If the benefits of using these platforms are meaningful, it could make a high end graphics card a requirement for competing. While this is also true for CPUs, CPU performance is not as varied or expensive compared to GPUs. We don't want a situation where your ability to compete is determined by your graphics card.
Will Foldit ever be open source? Currently, only Rosetta is open source, not Foldit. Source question
Unfortunately, this is unlikely. Please note that Rosetta itself is not open source, either.
The descriptions of remix and rebuild in jflat06's blog post raise some questions about how things work. First, if rebuild always works with a fragment length of 3, what does a rebuild of length 2 do? (A certain recipe defaults to starting with length 2.) Source question
In this case, rebuild is not actually inserting a fragment at all. It just places a cut, and then does a loop closure to close it again.
Could someone comment on the internal code:
LocalWiggleSequence in GUI versus structure.LocalWiggleSelected() in LUA:
Are they the same internally?
Or what would be the equivalent LUA function for this GUI one?
Extract from chat on 2017-01-13:
22:09 Wbertro TomTaylor5: converted "Wiggle by sheets" to LUA
22:09 TomTaylor5 Great
22:10 Wbertro but the code does not give the same results as the GUI one
22:10 Wbertro however it does not crash the client at the end
22:11 TomTaylor5 What would you like to hear first? The good news or the bad news?
22:11 Wbertro I think the GUI LocalWiggleSequence code is NOT the same as the LUA LocalWiggle code
22:11 TomTaylor5 That was probably the function I couldn't find.
22:12 Wbertro but the 1322 puzzle I tested them against is so sensitive that two runs don't give the same result twice
22:12 Wbertro I don't think it is a missing function
22:13 Wbertro it is simply DIFFERENT internal code, it seems
22:13 Wbertro I think I will ask on the next chat
They are using the same underlying procedure, but they differ in how they call it. The GUI script weirdly wiggles the residues sequentially, one at a time.
Thanks for the questions, everyone! We hope these additional answers help.( Posted by jflat06 82 704 | Thu, 02/23/2017 - 19:05 | 7 comments )