puzzle picture
1088: Blind Electron Density 12: N-terminus
Status: Closed

Summary

Name: 1088: Blind Electron Density 12: N-terminus
Status: Closed
Created: 05/15/2015
Points: 100
Expired: 05/22/2015 - 23:00
Difficulty: Intermediate
Description: Scientists have had difficulty solving the structure of this bacterial enzyme, which participates in the synthesis of certain antimicrobial compounds. The full protein is too large to model in Foldit, so we'll approach it in two separate puzzles; in this puzzle we'll focus on the N-terminal half of the protein. The starting solution is based on the structure of a homologous protein. See if you can find a solution that better fits the density!
Categories: Electron Density, Overall, Prediction

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2Beta Folders10,92982
3Void Crushers10,92666
4Russian team10,92253
5Go Science10,87642

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Comments

LociOiling's picture
User offline. Last seen 2 hours 51 min ago. Offline
Joined: 12/27/2012
Groups: Beta Folders
ligand at 141

This is a ligand puzzle, segment 141 has structure type "M".

I guess it's the stand-in for the rest of protein...?

LociOiling's picture
User offline. Last seen 2 hours 51 min ago. Offline
Joined: 12/27/2012
Groups: Beta Folders
or maybe not...

Opened this puzzle anew in another client. Guess what, not a ligand at 141. Tested puzzle in previous client, still reporting 141 as a ligand. YMMV

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons