Intermediate puzzles may require all of the Foldit tools, and assume players have finished the Campaign. Intermediate puzzles usually have additional Objectives, and may require you to fold a protein from scratch.


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Recent intermediate puzzles

Puzzle Status
2208: Monkeypox H3 Binder Design: Round 5 Open for the next 5 days
2207: SARS-CoV-2 helicase CACHE Challenge: Round 2 Open for the next about 3 hours
2205: BMPR Binder Design: Round 1 Closed since 2 days ago
2204: SARS-CoV-2 helicase CACHE Challenge: Round 1 Closed since 7 days ago
Design of the Month: September 2022 Closed since 7 days ago