In this category, players design new proteins for anything and everything -- from eco-friendly materials, to treatments for deadly diseases, to super-efficient enzymes. Players must design their protein so that it achieves the puzzle Objectives, and change its sequence so that the protein folds correctly.

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Recent design puzzles

Puzzle Status
Design of the Month: October 2022 Open for the next 27 days
2205: BMPR Binder Design: Round 1 Open for the next 1 day
Design of the Month: September 2022 Closed since 4 days ago
2202: Two-sided Strand Binder Design: Round 6 Closed since 6 days ago
2201: Monkeypox H3 Binder Design: Round 4 Closed since 11 days ago