In this category, players design new proteins for anything and everything -- from eco-friendly materials, to treatments for deadly diseases, to super-efficient enzymes. Players must design their protein so that it achieves the puzzle Objectives, and change its sequence so that the protein folds correctly.

Leaderboard: top design soloists

Recent design puzzles

Puzzle Status
Design of the Month: October 2022 Open for the next 24 days
2208: Monkeypox H3 Binder Design: Round 5 Open for the next 5 days
2205: BMPR Binder Design: Round 1 Closed since 2 days ago
Design of the Month: September 2022 Closed since 7 days ago
2202: Two-sided Strand Binder Design: Round 6 Closed since 9 days ago