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Lab Report #34: From DNA to protein
Coming join us in the lab to see how scientists make the proteins that players designed in Foldit. It all begins with an envelope full of custom DNA.
SPECIAL
- Protein designs in the lab
DESIGN OF THE MONTH
- This sandbox puzzle features a symmetric tetramer design by spvincent in Puzzle 2159. AlphaFold predicts the monomer unit will fold with high confidence, and an H-bond network at the interface should help prevent off-target assemblies. See for yourself in the Design of the Month sandbox puzzle.
Developer Preview Release Soon
Hey everyone,
We're about to post an update to the developer preview with some fixes and features. See the full list below!
Release Notes:
* Reworked the objectives panel.
* Reworked the puzzle menu.
* Added a visualization for the rest of the protein to the Trim Tool.
* Updated the icons for the trim/untrim actions.
* Trimmed solutions behave like cutpoint solutions and do not get credit until untrimmed.
* Several bug fixes for Education mode.
* Fix issue where language selection wasn't being properly saved.
Office hour!
Hey Foldit folks! We're going to be holding an Office Hour this Sunday, June 5th at 12 PM ET (4 pm GMT). It will be led by apetrides! Have questions or feedback about the new trim tool? Bring them to the office hour!
(Fri, 06/03/2022 - 01:53 | 0 comments)Lab Report #33: NEW Trim Tool = Monster Puzzles
The new Trim tool promises BIG things for Foldit. We're bringing bigger proteins to Foldit players, which means bigger contributions to protein folding research! Get the first scoop on upcoming Foldit features by joining devprev software updates.
NEWS
- The Trim tool
- Get devprev updates to test upcoming features
PUZZLE UPDATES
- Symmetric design
- Binder design
- Small molecule design
DESIGN OF THE MONTH
- A CD22 binder design by WBarme1234 in Puzzle 2141. When binding to target loops, look out for backbone polar atoms! This design makes the necessary H-bonds to avoid unsatisfied backbone BUNS. See for yourself in the Design of the Month sandbox puzzle.
