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Puzzle
Expires: 12/15/16 23:00:00
Top Group: Anthropic Dreams
Top Player: phi16
Top Score: 9,565
Categories: Overall, Prediction
The structure of this protein is still unknown. Secondary structure predictions (from PSIPRED) are marked on the starting structure, and provide clues about where the protein might form helices and sheets!
Puzzle
Expires: 12/13/16 18:00:00
Top Group: Beta Folders
Top Player: smilingone
Top Score: 9,547
Categories: Overall, Prediction
This is a throwback puzzle to the early days of Foldit. This toxin is found in green mamba venom, and blocks the flow of calcium ions that normally depolarize the muscle cell to induce muscle contraction. This protein contains six cysteine residues that oxidize to form three disulfide bonds. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been.
Puzzle
Expires: 12/10/16 23:00:00
5 comments
Top Group: Anthropic Dreams
Top Player: Galaxie
Top Score: 10,690
Categories: Design, Overall
Note: The starting structure has only 70 residues, but players are encouraged to add residues up to a total of 85! The disparity in residue number allows sharing of solutions from Puzzle 1302, which was posted with a faulty Residue Count filter and awarded no points. We apologize for any inconvenience!
Puzzle
Expires: 12/29/16 23:00:00
Top Group: Freeport Honors Biology 
Top Player: khendarg
Top Score: 9,201
Categories: Beginner
We are giving you this Parabacteroides Distasonis protein as an extended chain. The native is shown as a guide on this puzzle, so try using everything you have learned in the Intro levels to match the native fold. Hints and details are posted in the puzzle comments. For players with fewer than 150 global points.
Puzzle
Expires: 12/22/16 23:00:00
Top Group: FoldIt@Netherlands
Top Player: Old Chap
Top Score: 8,636
Categories: Beginner
We are giving you this currently unsolved short protein as an extended chain. It has only 48 residues and we're posting it with no secondary structure predictions. For players with fewer than 150 global points.
Puzzle
Expires: 12/15/16 23:00:00
Top Group: Go Science
Top Player: Sporeo
Top Score: 8,714
Categories: Beginner
This small unsolved Arabidopsis protein only has 59 residues and negatively controls the biosynthesis of starch in plants and regulates leaf and seed composition. We are giving you 5 starts for this puzzle. Resetting the puzzle will cycle through these 5 Zhang server predictions. They are also in the Alignment Tool so you can use partial threading as well as an extended chain. For players with fewer than 150 global points.

Closed

Puzzle
Expired: 12/14/16 23:00:00
10 comments
Top Group: Go Science
Top Player: Glen B
Top Score: 10,207
Categories:
Note: This puzzle was closed early due to a large number of crash reports.
Puzzle
Expired: 12/07/16 23:00:00
10 comments
Top Group: Anthropic Dreams
Top Player: Galaxie
Top Score: 9,429
Categories: Overall, Prediction
This is the monomor subunit for puzzle 1311. If puzzle 1311 is crashing for you, this puzzle can serve as a substitute for 1311. When we gather solutions, we will use both the solutions from this puzzle and from 1312.
Puzzle
Expired: 12/07/16 23:00:00
17 comments
Top Group: Go Science
Top Player: Bruno Kestemont
Top Score: 12,375
Categories:
Note: Due to a large number of crash reports, this puzzle has been made worth zero points. The puzzle will remain active, and players are encouraged continue playing the puzzle if they can. We will still analyze players solutions for scientific merit!
Puzzle
Expired: 11/29/16 03:00:00
3 comments
Top Group: Beta Folders
Top Player: smilingone
Top Score: 9,190
Categories:
This TB puzzle is summarized in http://fold.it/portal/node/2003049. It is a hexameric protein responsible for virulance factors in TB. We do have crystals and phase data, but none of our models work! Help us get a model to solve this structure.
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