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849a: De-novo Freestyle 34 Mutant: Hand-folding Round
Status: Closed


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bkoep's picture
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Secondary structure predictions

Here are the secondary structure predictions!
Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Alanines at residues 9 and 74 are highly predicted to be part of a sheet. However, the Alanines at residues 57-59 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

frood66's picture
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Groups: Marvin's bunch
the starting model appears to

the starting model appears to be missing the last 37 residues

bkoep's picture
User offline. Last seen 22 hours 28 min ago. Offline
Joined: 11/15/2012
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Thanks for the catch, that was my mistake. I've reposted the puzzle here: http://fold.it/portal/node/997118

gitwut's picture
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Joined: 05/18/2012
Groups: Contenders
Puzzle displays as being closed, points assigned

I'm guessing that it will be corrected at some point? It looks like it's already been factored into the category scores/rankings.

beta_helix's picture
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the current points will be removed and recalculated once that puzzle closes for good.

We apologize for the confusion with this one!

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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