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840: CASP ROLL Target R0046
Status: Closed

Summary

Name: 840: CASP ROLL Target R0046
Status: Closed
Created: 01/30/2014
Points: 100
Expired: 02/06/2014 - 23:00
Difficulty: Intermediate
Description: This unsolved CASP ROLL target has 128 residues. After this puzzle closes, there will be one more round with server predictions. See the puzzle comments for secondary structure predictions.
Categories: CASP ROLL, Overall, Prediction

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Comments

bkoep's picture
User offline. Last seen 12 hours 50 min ago. Offline
Joined: 11/15/2012
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Leucines at residues 77 & 78 are predicted to be part of a sheet. However, the Leucines at residues 20-22 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

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If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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