Nuetralize ED scoring and Disulfide Bridge scoring

Case number:845813-996546
Topic:Game: Tools
Opened by:karstenw
Opened on:Friday, January 3, 2014 - 18:59
Last modified:Sunday, April 13, 2014 - 20:09

Sometimes i'd like to work on these puzzles without them being grabbed at by their respective filters. I also want to chase the score without scoring being affected (of course the score would have a red line)by these filters.

(Fri, 01/03/2014 - 18:59  |  4 comments)

Joined: 09/21/2011

Sometimes a disulfide bridge catches at a particular angle and won't let go. The rest of the protein then conforms around those stubborn segments. Recent revisit puzzles have a lot of bridges. If I can get the protein to ignore the bridges until the protein is optimized, I might be able to align bridges at the end.

jeff101's picture
User offline. Last seen 2 hours 29 min ago. Offline
Joined: 04/20/2012
Groups: Go Science requested one-directional bands, like bumpers for cars. These would help keep the disulfides from bonding. also links to other suggestions for bands.

beta_helix's picture
User offline. Last seen 18 hours 56 min ago. Offline
Joined: 05/09/2008
Groups: None

Thanks for this suggestion, as there currently is no way to do that in the game!

Joined: 04/15/2012
Groups: Beta Folders

AS I've stated before, I'd like to see a way of playing the game with custom score parameters (both as a global representation, scores per segment, affecting coloring, etc.). It would also be helpful if tools could be affected by this (like CI). If there hasn't been a case made for this already, I'll go and add one soon...


Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons