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819: CASP ROLL Target R0043
Status: Closed


Name: 819: CASP ROLL Target R0043
Status: Closed
Created: 12/05/2013
Points: 100
Expired: 12/12/2013 - 22:00
Difficulty: Intermediate
Description: This unsolved CASP ROLL target has 163 residues. There are no homologs, so we are starting you from an extended chain. After this puzzle closes, there will be one more round with server predictions. See the puzzle comments for secondary structure predictions.
Categories: CASP ROLL, Overall, Prediction

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bkoep's picture
User offline. Last seen 5 hours 27 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Isoleucines at residues 7 & 8 are predicted to be part of a sheet. However, the Isoleucines at residues 151 & 155 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

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