Help the Worcester Polytechnic Institute with this unsolved protein!
Our lab has been contacted by scientists at the Worcester Polytechnic Institute working on an unsolved viral protein. They are hoping you can help them solve the structure of this important protein, here is their message to you:
Apoptin is a viral protein from the Chicken Anemia Virus (CAV). It is of special interest because it selectively targets transform (Cancer) cells and causes apoptosis (programmed cell death). However we do not know why it selectively kills cancer cells, a function which is tied to its 3D structure. Solving this protein structure would greatly advance research into apoptin’s functionality and development as a method to treat cancer.
We are giving you 5 Zhang Server models to start with for Puzzle 731b: Unsolved Chicken Anemia Virus Protein
Here is a link to the Zhang Server webpage for more details:
Attached is an article discussing the function properties of Apoptin.