puzzle picture
BETA 60res trimer
Status: Closed


Name: BETA 60res trimer
Status: Closed
Created: 04/29/2013
Points: 0
Expired: 05/08/2013 - 16:00
Difficulty: Advanced
Description: This is a 60 residue symmetric trimer design puzzle. The score function has been modified from the pervious design puzzles in order to alleviate the need for the slow filters. We would like you to stress test the puzzle to see if it exhibits any of the pathologies the filters were there to address. A symmetric protein relies not only on how well folded each part is, but also on how well they interface together; see the latest blogpost about this. There is only one filter enabled on this puzzle. It is very fast to compute so it should not interfere with the speed of the tools. The ResidueIE filter ensures PHY, TYR, and TRP residues are scoring well.

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marie_s's picture
User offline. Last seen 1 year 41 weeks ago. Offline
Joined: 05/18/2008
Groups: None
how can we have the bonus?

it is said "0 or 1 bonus gained".
The puzzle works globally well.
Few wiggles frozen.
many many arginines.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons