puzzle picture
698 (<15): Human cancer protein interaction network target
Status: Closed

Summary

Name: 698 (<15): Human cancer protein interaction network target
Status: Closed
Created: 04/05/2013
Points: 100
Expired: 04/17/2013 - 08:00
Difficulty: Beginner
Description: The solution structure of this dead ringer-like protein has already been solved using NMR, but the crystal structure has yet to be released. We are giving you all 20 models from the NMR ensemble. Every time you reset the puzzle it will cycle through these 20 structures and they are available in the Alignment Tool so you can use partial threading between them. We look forward to seeing how close to the crystal structure you are able to get! For players with fewer than 15 global points.
Categories: Overall, Prediction

Top Groups

Top Soloists

RankPlayerGroupScorePoints
1Studebakerhawk 98 2294  11,337100
2MyNameIsNeo 98 2294  11,26899
3rsladew 98 2294 Richard Dawkins Foundation11,22197
4shawn42 98 2294  11,22096
5roarshock 98 2294  11,18494


Need this puzzle? Log in to download.  

Comments

beta_helix's picture
User offline. Last seen 15 hours 33 min ago. Offline
Joined: 05/09/2008
Groups: None
START HERE:

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

Additional information on partial threading here:
http://fold.it/portal/node/989193#comment-9965
_____________________________

If you want to fold proteins, know that there are many way to play and this variety is the main value of Foldit :
- try all puzzles not only "beginners" one,
- fold first the ones you like the most,
- try by yourself to understand what works and what doesn't,
- make your own strategy and at least try more than one, here some other strategies to play QTTN http://foldit.wikia.com/wiki/101_-_Puzzle_Levels_and_Types,
- ask for tips in global when you think you doesn't understand something.

Make sure you have followed these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing
before starting this puzzle.

marie_s's picture
User offline. Last seen 33 weeks 4 days ago. Offline
Joined: 05/18/2008
Groups: None
this puzzle is an alignment puzzle

So make sure you have also followed the tutorials:
- basic threading
- alignin sequence

you can also see on the wiki these pages :
http://foldit.wikia.com/wiki/The_Alignment_Tool
http://foldit.wikia.com/wiki/Alignment_Tool

User login
Download links:
  Windows    OSX    Linux  
Windows
(7/8/10)
OSX
(10.12 or later)
Linux
(64-bit)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Social Media


Search
Only search fold.it
Other Games: Mozak
Recommend Foldit
Topics
Top New Users
Sitemap

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons