puzzle picture
639: De-novo Freestyle 17
Status: Closed

Summary

Name: 639: De-novo Freestyle 17
Status: Closed
Created: 10/10/2012
Points: 100
Expired: 10/18/2012 - 08:00
Difficulty: Advanced
Description: This currently unsolved short protein does not have any templates that we can use, so to prepare for CASP ROLL we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.
Categories: Overall, Prediction

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RankGroupScorePoints
1Anthropic Dreams10,780100
2Contenders10,75185
3Beta Folders10,71372
4Void Crushers10,70061
5foldeRNA10,58951

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Comments

beta_helix's picture
User offline. Last seen 3 weeks 5 days ago. Offline
Joined: 05/09/2008
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 85 & 44 are highly predicted to be part of a sheet. However, the Valines at residues 12 & 102 are not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Microsoft, Adobe, RosettaCommons