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615: CASP10 Refinement Puzzle: TR754
Status: Closed
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Soloists
| 1 | SimplySue 61 120 | Anthropic Dreams | 9,434 | 100 | | 2 | harp 39 110 | Anthropic Dreams | 9,417 | 98 | | 3 | BitSpawn 140 710 | Anthropic Dreams | 9,412 | 96 | | 4 | mimi 13 19 | Contenders | 9,410 | 94 | | 5 | smilingone 9 20 | Beta Folders | 9,373 | 92 | | 6 | gmn 5 1 | Anthropic Dreams | 9,363 | 90 | | 7 | stg123123 140 112 | Beta Folders | 9,357 | 89 | | 8 | micheldeweerd 116 61 | foldeRNA | 9,354 | 87 | | 9 | gramps 71 27 | Anthropic Dreams | 9,351 | 85 | | 10 | bertro 35 11 | foldeRNA | 9,345 | 83 | | 11 | Mike Tate 140 7459 | putting the eat in meat | 9,342 | 81 | | 12 | doug.ehlert 134 346 | Contenders | 9,341 | 80 | | 13 | mat747 140 362 | Void Crushers | 9,335 | 78 | | 14 | Bletchley Park 11 7 | Contenders | 9,330 | 76 | | 15 | pauldunn 28 22 | Go Science | 9,327 | 75 | | 16 | Lindata 23 118 | Anthropic Dreams | 9,326 | 73 | | 17 | marie_s 140 39 | | 9,322 | 71 | | 18 | mottiger 140 509 | Anthropic Dreams | 9,320 | 70 | | 19 | dembones 79 134 | Contenders | 9,319 | 68 | | 20 | Madde 107 32 | Void Crushers | 9,310 | 67 | | 21 | drjr 103 42 | Anthropic Dreams | 9,304 | 65 | | 22 | meatexplosion 93 25 | Anthropic Dreams | 9,295 | 64 | | 23 | Timo van&n... 51 5 | Void Crushers | 9,295 | 62 | | 24 | gdnskye 82 79 | Anthropic Dreams | 9,293 | 61 | | 25 | Flagg65a 140 47 | | 9,292 | 60 |
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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=211
Note that the organizers gave us this hint:
"Starting model's GDT_TS=77."
GDT_TS=77 essentially means that ONLY 77% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valine at residue 58 is highly predicted to be part of a helix. However, the Valine at residue 2 is predicted to be in a sheet.