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610: CASP10 Refinement Puzzle: TR750
Status: Closed
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Summary
| Name: | 610: CASP10 Refinement Puzzle: TR750 |
|---|---|
| Status: | Closed |
| Created: | 08/01/2012 |
| Points: | 100 |
| Difficulty: | Intermediate |
| Description: | This is the twentieth CASP10 Refinement Target. We've been told that ~77% of this model matches the native, so you'll need to refine ~23% of the structure! More info in the puzzle comments. |
| Categories: | CASP, Overall, Prediction |
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Please note that the Cut Tool is available on all puzzles from now on!
This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=202
The CASP10 organizers gave us this hint:
"Starting model GDT_TS=77."
GDT_TS=77 essentially means that 77% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valines at residues 84 & 176 are highly predicted to be part of a helix. However, the Valines at residues 64-65 & 99 are predicted to be part of a sheet.