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605: CASP10 Refinement Puzzle: TR710
Status: Closed
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Soloists
| 1 | Galaxie 1 3 | Anthropic Dreams | 13,089 | 100 | | 2 | meatexplosion 93 25 | Anthropic Dreams | 13,082 | 98 | | 3 | O Seki To 46 18 | Team Hungary | 13,064 | 95 | | 4 | gmn 5 1 | Anthropic Dreams | 13,058 | 93 | | 5 | Madde 107 32 | Void Crushers | 13,057 | 90 | | 6 | pauldunn 28 22 | Go Science | 13,051 | 88 | | 7 | BitSpawn 140 710 | Anthropic Dreams | 13,047 | 85 | | 8 | christioanchauvin 49 38 | L'Alliance Francophone | 13,043 | 83 | | 9 | CKnight 140 7459 | Go Science | 13,043 | 80 | | 10 | stg123123 140 112 | Beta Folders | 13,028 | 78 | | 11 | bertro 35 11 | foldeRNA | 13,027 | 76 | | 12 | doug.ehlert 134 346 | Contenders | 13,024 | 74 | | 13 | harp 39 110 | Anthropic Dreams | 13,024 | 72 | | 14 | enszyme 125 89 | L'Alliance Francophone | 13,019 | 70 | | 15 | johnmitch 140 12 | | 13,014 | 68 | | 16 | smilingone 9 20 | Beta Folders | 12,992 | 66 | | 17 | bendbob 140 92 | Anthropic Dreams | 12,992 | 64 | | 18 | jakbinimbol 140 6 | | 12,963 | 62 | | 19 | SimplySue 61 120 | Anthropic Dreams | 12,960 | 59 | | 20 | hpaege 140 686 | | 12,960 | 57 | | 21 | gramps 71 27 | Anthropic Dreams | 12,959 | 55 | | 22 | Jim Fraser 140 71 | Contenders | 12,958 | 53 | | 23 | mimi 13 19 | Contenders | 12,952 | 52 | | 24 | Flagg65a 140 47 | | 12,938 | 50 | | 25 | Timo van&n... 51 5 | Void Crushers | 12,934 | 49 |
Comments
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| marie_s 140 39 | 718: Hand-Foldi...ore | 14,474 | | meatexplosion 93 25 | 717: CASP ROLL ...034 | 11,314 | | bertro 35 11 | Beginner Puzzle...xin | 9,983 | | fold.like.a.c...ion 140 534 | Beginner Puzzle...xin | 9,841 | | yreeen 140 1723 | Beginner Puzzle...xin | 9,580 | | Dorothy 140 7459 | 716 (<15): Two ...ant | 8,679 | | Bjro 140 486 | 716 (<150): Two...ant | 8,763 | | pauldunn 28 22 | 716: Two chains...ant | 8,944 | | Susume 140 14 | 714: 5-year-ann...012 | 11,153 | | Mark- 140 94 | 713: 5-year-ann...011 | 13,310 |
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| marie_s 140 39 | 718: Hand-Foldi...ore | 14,474 | | meatexplosion 93 25 | 717: CASP ROLL ...034 | 11,314 | | bertro 35 11 | Beginner Puzzle...xin | 9,983 | | fold.like.a.c...ion 140 534 | Beginner Puzzle...xin | 9,841 | | yreeen 140 1723 | Beginner Puzzle...xin | 9,580 | | Dorothy 140 7459 | 716 (<15): Two ...ant | 8,679 | | Bjro 140 486 | 716 (<150): Two...ant | 8,763 | | pauldunn 28 22 | 716: Two chains...ant | 8,944 | | Susume 140 14 | 714: 5-year-ann...012 | 11,153 | | Mark- 140 94 | 713: 5-year-ann...011 | 13,310 |
| Anthropic Dreams | 718: Hand-Foldi...ore | 14,474 | | Anthropic Dreams | 717: CASP ROLL ...034 | 11,316 | | Beta Folders | Beginner Puzzle...xin | 9,985 | | Anthropic Dreams | Beginner Puzzle...xin | 9,567 | | Anthropic Dreams | Beginner Puzzle...xin | 8,938 | | NWFSC CHS | 716 (<15): Two ...ant | 8,631 | | Contenders | 716 (<150): Two...ant | 8,699 | | Go Science | 716: Two chains...ant | 8,944 | | Anthropic Dreams | 714: 5-year-ann...012 | 11,156 | | Contenders | 713: 5-year-ann...011 | 13,310 |
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Please note that the Cut Tool is available on this puzzle!
This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=188
The CASP10 organizers gave us this hint:
"Starting model GDT_TS=75."
GDT_TS=75 essentially means that 75% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valines at residues 19, 52, 85, 145 & 177 are highly predicted to be part of a helix. However, the Valines at residues 96 & 100 are not.