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603: CASP10 Refinement Puzzle: TR705
Status: Closed
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Soloists
| 1 | Hanto_FZ140E_4G 44 58 | | 10,479 | 100 | | 2 | smilingone 9 20 | Beta Folders | 10,458 | 98 | | 3 | johnmitch 140 12 | | 10,438 | 95 | | 4 | gmn 5 1 | Anthropic Dreams | 10,414 | 93 | | 5 | meatexplosion 93 25 | Anthropic Dreams | 10,352 | 90 | | 6 | BitSpawn 140 710 | Anthropic Dreams | 10,347 | 88 | | 7 | mbinfield 128 2213 | Go Science | 10,346 | 86 | | 8 | bertro 35 11 | foldeRNA | 10,339 | 83 | | 9 | hansvandenhof 20 9 | foldeRNA | 10,337 | 81 | | 10 | stg123123 140 112 | Beta Folders | 10,326 | 79 | | 11 | gramps 71 27 | Anthropic Dreams | 10,321 | 77 | | 12 | doug.ehlert 134 346 | Contenders | 10,319 | 75 | | 13 | pauldunn 28 22 | Go Science | 10,315 | 72 | | 14 | Galaxie 1 3 | Anthropic Dreams | 10,310 | 70 | | 15 | mottiger 140 509 | Anthropic Dreams | 10,309 | 69 | | 16 | christioanchauvin 49 38 | L'Alliance Francophone | 10,299 | 67 | | 17 | CharlieFortsCon... 84 108 | Contenders | 10,295 | 65 | | 18 | enszyme 125 89 | L'Alliance Francophone | 10,294 | 63 | | 19 | Timo van&n... 51 5 | Void Crushers | 10,282 | 61 | | 20 | crpainter 140 84 | | 10,272 | 59 | | 21 | Madde 107 32 | Void Crushers | 10,267 | 58 | | 22 | drjr 103 42 | Anthropic Dreams | 10,265 | 56 | | 23 | utaca 74 31 | Void Crushers | 10,264 | 54 | | 24 | Susume 140 14 | Anthropic Dreams | 10,259 | 53 | | 25 | mat747 140 362 | Void Crushers | 10,258 | 51 |
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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=192
Note that the organizers gave us this hint:
"Starting model GDT_TS=65."
GDT_TS=65 essentially means that ONLY 65% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valines at residues 19, 20 & 76 are highly predicted to be part of a sheet. However, the Valine at residue 38 is predicted to be anything.