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603: CASP10 Refinement Puzzle: TR705
Status: Closed
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Groups
| 1 | Beta Folders | 10,458 | 100 | | 2 | Anthropic Dreams | 10,429 | 78 | | 3 | Contenders | 10,383 | 60 | | 4 | Go Science | 10,355 | 45 | | 5 | foldeRNA | 10,339 | 34 | | 6 | L'Alliance Francophone | 10,301 | 25 | | 7 | Void Crushers | 10,282 | 18 | | 8 | FoldIt@Netherlands | 10,256 | 13 | | 9 | Team Hungary | 10,167 | 9 | | 10 | Mojo Risin' | 10,085 | 6 | | 11 | Russian team | 10,077 | 4 | | 12 | Gargleblasters | 10,011 | 3 | | 13 | SETI.Germany | 9,893 | 2 | | 14 | Natural Abilities | 9,821 | 1 | | 15 | Another Hour Another Point | 9,796 | 1 | | 16 | Richard Dawkins Foundation | 9,729 | 1 | | 17 | 7Monkeys | 9,698 | 1 | | 18 | Czech National Team | 9,612 | 1 | | 19 | Team Canada | 9,439 | 1 | | 20 | Team China | 9,351 | 1 | | 21 | DSN @ Home | 9,111 | 1 | | 22 | Geekdo | 9,108 | 1 | | 23 | Nerdfighters | 9,007 | 1 | | 24 | null pointer exception | 7,269 | 1 | | 25 | test_group1 | 6,837 | 1 |
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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=192
Note that the organizers gave us this hint:
"Starting model GDT_TS=65."
GDT_TS=65 essentially means that ONLY 65% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valines at residues 19, 20 & 76 are highly predicted to be part of a sheet. However, the Valine at residue 38 is predicted to be anything.