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598: CASP10 Refinement Puzzle: TR712
Status: Closed
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Soloists
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| 176 | mtimmons 75 1437 | | 11,906 | 1 | | 177 | mooses 75 1437 | | 11,898 | 1 | | 178 | firejuggler 75 1437 | Void Crushers | 11,898 | 1 | | 179 | ch00215 75 1437 | | 11,877 | 1 | | 180 | crawlee34225 75 1437 | | 11,870 | 1 | | 181 | ofc2000 75 1437 | | 11,855 | 1 | | 182 | birdy_ssr 75 1437 | | 11,844 | 1 | | 183 | lb494 75 1437 | | 11,840 | 1 | | 184 | Lena70 75 1437 | | 11,826 | 1 | | 185 | grunge28 75 1437 | | 11,819 | 1 | | 186 | Arne Heessels 75 280 | | 11,814 | 1 | | 187 | FScot 75 1437 | | 11,813 | 1 | | 188 | nickbobbitt2015 75 1437 | | 11,813 | 1 | | 189 | miss wanr 75 1437 | foldeRNA | 11,766 | 1 | | 190 | blafoot 75 1437 | | 11,761 | 1 | | 191 | Datstandin 75 1437 | Anthropic Dreams | 11,647 | 1 | | 192 | remisphere 75 1437 | | 11,616 | 1 | | 193 | OptimusBatman 75 1437 | | 11,500 | 1 | | 194 | dbuske 75 1437 | Geekdo | 11,393 | 1 | | 195 | tigger3370 75 1437 | | 11,197 | 1 | | 196 | yorinagak 75 1437 | | 11,111 | 1 | | 197 | sciencenerd13 75 1437 | | 11,091 | 1 | | 198 | aspadistra 75 727 | DSN @ Home | 11,054 | 1 | | 199 | MalcolmW 75 1437 | | 10,877 | 1 | | 200 | packer 75 1437 | Go Science | 10,802 | 1 | Need this puzzle? Log in to download.
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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=170
Note that the organizers gave us this hint:
"Starting model GDT_TS=92. Regions worth specific attention: 43-52, 79-92, 104-118."
GDT_TS=92 essentially means that 92% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valines at residues 18, 20, 42 & 148 are highly predicted to be part of a sheet. However, the Valine at residue 105 is predicted to be in anything.