puzzle picture
598: CASP10 Refinement Puzzle: TR712
Status: Closed

Soloists

RankPlayerGroupScorePoints
176mtimmons 75 1437  11,9061
177mooses 75 1437  11,8981
178firejuggler 75 1437 Void Crushers11,8981
179ch00215 75 1437  11,8771
180crawlee34225 75 1437  11,8701
181ofc2000 75 1437  11,8551
182birdy_ssr 75 1437  11,8441
183lb494 75 1437  11,8401
184Lena70 75 1437  11,8261
185grunge28 75 1437  11,8191
186Arne Heessels 75 280  11,8141
187FScot 75 1437  11,8131
188nickbobbitt2015 75 1437  11,8131
189miss wanr 75 1437 foldeRNA11,7661
190blafoot 75 1437  11,7611
191Datstandin 75 1437 Anthropic Dreams11,6471
192remisphere 75 1437  11,6161
193OptimusBatman 75 1437  11,5001
194dbuske 75 1437 Geekdo11,3931
195tigger3370 75 1437  11,1971
196yorinagak 75 1437  11,1111
197sciencenerd13 75 1437  11,0911
198aspadistra 75 727 DSN @ Home11,0541
199MalcolmW 75 1437  10,8771
200packer 75 1437 Go Science10,8021


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beta_helix's picture
User offline. Last seen 1 hour 51 min ago. Offline
Joined: 05/09/2008
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More info here:

This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=170

Note that the organizers gave us this hint:

"Starting model GDT_TS=92. Regions worth specific attention: 43-52, 79-92, 104-118."

GDT_TS=92 essentially means that 92% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 18, 20, 42 & 148 are highly predicted to be part of a sheet. However, the Valine at residue 105 is predicted to be in anything.

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