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598: CASP10 Refinement Puzzle: TR712
Status: Closed
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Soloists
126 | Uwe 75 1437 | | 12,377 | 1 | 127 | Tlaloc 75 1437 | Mojo Risin' | 12,377 | 1 | 128 | abiogenesis 75 73 | | 12,371 | 1 | 129 | Susume 75 727 | Anthropic Dreams | 12,350 | 1 | 130 | deLaCeiba 75 1437 | | 12,341 | 1 | 131 | justjustin 75 1437 | Anthropic Dreams | 12,333 | 1 | 132 | c1261015 75 1437 | | 12,332 | 1 | 133 | dublinone 75 1437 | | 12,328 | 1 | 134 | phi16 9 30 | Anthropic Dreams | 12,314 | 1 | 135 | ourtown 75 1437 | | 12,310 | 1 | 136 | Kevonni 75 1437 | | 12,300 | 1 | 137 | Ben666 75 1437 | | 12,287 | 1 | 138 | aendgraend 75 1437 | SETI.Germany | 12,285 | 1 | 139 | GreekCivilization 75 1437 | | 12,281 | 1 | 140 | sbea3 75 1437 | | 12,279 | 1 | 141 | Heinermann 75 1437 | Anthropic Dreams | 12,273 | 1 | 142 | bluecrab 75 1437 | | 12,254 | 1 | 143 | CoachB 75 1437 | | 12,243 | 1 | 144 | HRM Chatzi... 75 1437 | Eὕρηκα! Heureka! | 12,240 | 1 | 145 | kastberg 75 1437 | Go Science | 12,235 | 1 | 146 | el-don 75 1437 | | 12,225 | 1 | 147 | Bautho 75 409 | SETI.Germany | 12,208 | 1 | 148 | KingFrog 75 1437 | Anthropic Dreams | 12,206 | 1 | 149 | aleber 75 1437 | | 12,195 | 1 | 150 | SouperGenious 75 1437 | | 12,189 | 1 | Need this puzzle? Log in to download.
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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=170
Note that the organizers gave us this hint:
"Starting model GDT_TS=92. Regions worth specific attention: 43-52, 79-92, 104-118."
GDT_TS=92 essentially means that 92% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valines at residues 18, 20, 42 & 148 are highly predicted to be part of a sheet. However, the Valine at residue 105 is predicted to be in anything.