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598: CASP10 Refinement Puzzle: TR712
Status: Closed
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Soloists
76 | manu8170 46 90 | | 12,583 | 5 | 77 | RabidNimravid 46 1399 | Anthropic Dreams | 12,582 | 5 | 78 | BootsMcGraw 11 9 | Contenders | 12,579 | 4 | 79 | Lindata 46 1399 | Anthropic Dreams | 12,574 | 4 | 80 | heather-1 46 96 | | 12,570 | 4 | 81 | weurhartdezirez 46 1399 | Freedom Folders | 12,567 | 4 | 82 | jobo0502 46 22 | L'Alliance Francophone | 12,565 | 4 | 83 | Jesse Pinkman 46 1399 | | 12,563 | 4 | 84 | keithv 46 1399 | Anthropic Dreams | 12,560 | 3 | 85 | WBarme1234 46 23 | | 12,559 | 3 | 86 | Tony Origami 46 1399 | | 12,553 | 3 | 87 | blob_folder 46 1399 | 7Monkeys | 12,550 | 3 | 88 | jermainiac 46 1399 | Anthropic Dreams | 12,547 | 3 | 89 | Mike Cassidy 46 91 | Void Crushers | 12,545 | 3 | 90 | mitarcher 46 1399 | | 12,543 | 3 | 91 | Rispervisper 46 1399 | | 12,541 | 2 | 92 | Merf 46 89 | | 12,536 | 2 | 93 | drjr 46 1038 | Anthropic Dreams | 12,519 | 2 | 94 | Ch Garnier 46 1399 | L'Alliance Francophone | 12,517 | 2 | 95 | JasperD 46 1399 | foldeRNA | 12,512 | 2 | 96 | anne romaine 46 1399 | | 12,512 | 2 | 97 | Psych0Active 46 1399 | | 12,503 | 2 | 98 | Chris67 46 1399 | | 12,502 | 2 | 99 | lynnai 46 1399 | Anthropic Dreams | 12,492 | 2 | 100 | DrMistry 46 1399 | | 12,488 | 2 | Need this puzzle? Log in to download.
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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=170
Note that the organizers gave us this hint:
"Starting model GDT_TS=92. Regions worth specific attention: 43-52, 79-92, 104-118."
GDT_TS=92 essentially means that 92% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valines at residues 18, 20, 42 & 148 are highly predicted to be part of a sheet. However, the Valine at residue 105 is predicted to be in anything.