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598: CASP10 Refinement Puzzle: TR712
Status: Closed
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Soloists
51 | larry25427 75 1437 | | 12,664 | 15 | 52 | Neroje 75 1437 | FoldIt@Netherlands | 12,654 | 14 | 53 | silverberg 75 1437 | | 12,652 | 13 | 54 | malthreSC 75 1437 | | 12,652 | 13 | 55 | goastano 75 1437 | L'Alliance Francophone | 12,648 | 12 | 56 | christioanchauvin 75 31 | L'Alliance Francophone | 12,647 | 12 | 57 | brow42 75 1437 | | 12,647 | 11 | 58 | harvardman 75 1437 | Anthropic Dreams | 12,646 | 11 | 59 | ViJay7019 75 1437 | FoldIt@Netherlands | 12,645 | 10 | 60 | auntdeen 75 1437 | Anthropic Dreams | 12,644 | 10 | 61 | tallguy-13088 75 1437 | | 12,635 | 9 | 62 | AIDA64 75 1437 | | 12,633 | 9 | 63 | pgiles 75 1437 | | 12,621 | 9 | 64 | AsDawnBreaks 75 1437 | | 12,619 | 8 | 65 | djag 75 1437 | Contenders | 12,616 | 8 | 66 | Tyggy Too 75 1437 | Anthropic Dreams | 12,611 | 8 | 67 | jtollenaar 75 1437 | | 12,606 | 7 | 68 | weitzen 75 1437 | | 12,605 | 7 | 69 | westrel3 75 1437 | Anthropic Dreams | 12,600 | 7 | 70 | Jim Fraser 75 1437 | Contenders | 12,596 | 6 | 71 | bamh 75 51 | | 12,591 | 6 | 72 | Grom 75 1437 | Russian team | 12,588 | 6 | 73 | jdretired 75 1437 | | 12,586 | 6 | 74 | crpainter 75 1437 | | 12,586 | 5 | 75 | jamiexq 25 62 | Anthropic Dreams | 12,586 | 5 | Need this puzzle? Log in to download.
Comments
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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=170
Note that the organizers gave us this hint:
"Starting model GDT_TS=92. Regions worth specific attention: 43-52, 79-92, 104-118."
GDT_TS=92 essentially means that 92% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valines at residues 18, 20, 42 & 148 are highly predicted to be part of a sheet. However, the Valine at residue 105 is predicted to be in anything.