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598: CASP10 Refinement Puzzle: TR712
Status: Closed
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Soloists
26 | gitwut 46 1295 | Contenders | 12,791 | 43 | 27 | enszyme 46 1295 | L'Alliance Francophone | 12,781 | 41 | 28 | pauldunn 46 1295 | Go Science | 12,781 | 40 | 29 | rsosborne 46 1295 | foldeRNA | 12,776 | 38 | 30 | jakbinimbol 46 1295 | | 12,773 | 37 | 31 | harp 46 1295 | Anthropic Dreams | 12,768 | 36 | 32 | spmm 46 246 | Void Crushers | 12,763 | 34 | 33 | cbwest 46 706 | foldeRNA | 12,743 | 33 | 34 | gramps 46 1295 | Anthropic Dreams | 12,737 | 31 | 35 | yoyo washington 46 1295 | L'Alliance Francophone | 12,732 | 30 | 36 | froggs554 46 1295 | | 12,731 | 28 | 37 | mat747 46 1295 | Void Crushers | 12,730 | 27 | 38 | bobcat 46 1295 | | 12,729 | 26 | 39 | hpaege 46 1295 | | 12,725 | 25 | 40 | Flagg65a 46 1295 | | 12,725 | 24 | 41 | fishercat 46 1295 | Anthropic Dreams | 12,722 | 23 | 42 | mottiger 46 1295 | Anthropic Dreams | 12,722 | 23 | 43 | onursavas 46 1295 | Needles and Pins | 12,715 | 22 | 44 | spdenne 46 624 | Void Crushers | 12,713 | 21 | 45 | CharlieFortsCon... 46 1295 | Contenders | 12,704 | 20 | 46 | pvc78 46 1295 | | 12,694 | 19 | 47 | frostschutz 46 117 | | 12,679 | 18 | 48 | ErichVonSterich 46 1295 | Anthropic Dreams | 12,677 | 18 | 49 | Angus 46 1295 | Beta Folders | 12,676 | 17 | 50 | Close At&n... 46 1295 | | 12,673 | 16 | Need this puzzle? Log in to download.
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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=170
Note that the organizers gave us this hint:
"Starting model GDT_TS=92. Regions worth specific attention: 43-52, 79-92, 104-118."
GDT_TS=92 essentially means that 92% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valines at residues 18, 20, 42 & 148 are highly predicted to be part of a sheet. However, the Valine at residue 105 is predicted to be in anything.