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598: CASP10 Refinement Puzzle: TR712
Status: Closed
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Evolvers
1 | BitSpawn 46 143 | Anthropic Dreams | 13,022 | 100 | 2 | meatexplosion 46 1603 | Anthropic Dreams | 13,020 | 97 | 3 | ErichVonSterich 46 1603 | Anthropic Dreams | 13,018 | 94 | 4 | gitwut 46 160 | Contenders | 12,994 | 91 | 5 | lamoille 46 1603 | Anthropic Dreams | 12,989 | 88 | 6 | keithv 46 1603 | Anthropic Dreams | 12,986 | 85 | 7 | SimplySue 46 1603 | Anthropic Dreams | 12,982 | 83 | 8 | phi16 9 30 | Anthropic Dreams | 12,980 | 80 | 9 | Bletchley Park 8 7 | Contenders | 12,966 | 77 | 10 | westrel3 46 1603 | Anthropic Dreams | 12,957 | 75 | 11 | barbaranne 46 1603 | Anthropic Dreams | 12,956 | 72 | 12 | randomlil 46 1603 | Beta Folders | 12,943 | 70 | 13 | jamiexq 16 35 | Anthropic Dreams | 12,943 | 68 | 14 | mimi 46 210 | Contenders | 12,938 | 65 | 15 | smilingone 46 194 | Beta Folders | 12,937 | 63 | 16 | Angus 46 1603 | Beta Folders | 12,930 | 61 | 17 | spdenne 46 148 | Void Crushers | 12,905 | 59 | 18 | Ribo-soma 46 1603 | Hun-Magyar Csapat | 12,886 | 57 | 19 | O Seki To 46 292 | Hun-Magyar Csapat | 12,882 | 55 | 20 | histon 46 949 | Hun-Magyar Csapat | 12,879 | 53 | 21 | Wildcat777 46 1603 | Void Crushers | 12,852 | 51 | 22 | alwen 46 554 | Anthropic Dreams | 12,800 | 49 | 23 | JasperD 46 554 | foldeRNA | 12,696 | 48 | 24 | harvardman 46 554 | Anthropic Dreams | 12,662 | 46 | 25 | Rita_Gat 46 1603 | Russian team | 12,625 | 44 | Need this puzzle? Log in to download.
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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=170
Note that the organizers gave us this hint:
"Starting model GDT_TS=92. Regions worth specific attention: 43-52, 79-92, 104-118."
GDT_TS=92 essentially means that 92% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valines at residues 18, 20, 42 & 148 are highly predicted to be part of a sheet. However, the Valine at residue 105 is predicted to be in anything.