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586: Large CASP10 Refinement Puzzle: TR681
Status: Closed
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Evolvers
| 1 | lamoille 24 202 | Anthropic Dreams | 13,487 | 100 | | 2 | Hanto_FZ140E_4G 44 58 | Go Science | 13,460 | 98 | | 3 | B_2 140 7459 | Go Science | 13,435 | 95 | | 4 | krulon 140 7459 | foldeRNA | 13,406 | 90 | | 5 | JasperD 65 83 | foldeRNA | 13,402 | 87 | | 6 | mimi 13 19 | Contenders | 13,386 | 84 | | 7 | gitwut 7 10 | Contenders | 13,368 | 82 | | 8 | Bletchley Park 11 7 | Contenders | 13,289 | 80 | | 9 | BootsMcGraw 12 26 | Contenders | 13,286 | 77 | | 10 | martinzblavy 21 4 | Contenders | 13,278 | 75 | | 11 | Rav3n_pl 140 180 | Anthropic Dreams | 13,275 | 73 | | 12 | spvincent 58 95 | Contenders | 13,275 | 71 | | 13 | dembones 79 134 | Contenders | 13,245 | 69 | | 14 | barbaranne 14 178 | Anthropic Dreams | 13,242 | 67 | | 15 | Lindata 23 118 | Anthropic Dreams | 13,241 | 65 | | 16 | ErichVonSterich 64 162 | Anthropic Dreams | 13,239 | 63 | | 17 | jamiexq 3 69 | Anthropic Dreams | 13,239 | 61 | | 18 | keithv 140 7459 | Anthropic Dreams | 13,239 | 59 | | 19 | Dixie2 118 2262 | foldeRNA | 13,187 | 57 | | 20 | alwen 6 81 | Anthropic Dreams | 12,882 | 54 | | 21 | harvardman 32 143 | Anthropic Dreams | 12,880 | 52 | | 22 | phi16 8 44 | Anthropic Dreams | 12,880 | 50 | | 23 | westrel3IRC 140 7459 | Anthropic Dreams | 12,858 | 49 | | 24 | smilingone 9 20 | | 12,760 | 47 | | 25 | svenmh 57 86 | foldeRNA | 12,359 | 46 |
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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=140
Note that the organizers gave us this hint:
"Starting model GDT_TS=78."
GDT_TS=78 essentially means that 78% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test
We believe that MULTICOM-CONSTRUCT_TS3.pdb is identical to the refinement model.
Here is the sequence logo predicted by the SAM server:
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Leucines at residues 14-15 are highly predicted to be in a helix. However, the Leucines at residues 54 & 86 are predicted to be part of a sheet.