Scoring artifact? --- 571

Case number:671071-992899
Topic:Game: Other
Opened by:BootsMcGraw
Status:Resolved
Assigned:tamirh
Priority:3
Type:Bug
Opened on:Saturday, June 9, 2012 - 02:56
Last modified:Tuesday, January 8, 2013 - 05:35

I'm not sure if any of the other top scorers on puzzle #571 are seeing this, but I am finding that saturating this helix with aromatics is producing the highest scores.

I doubt highly that a real-life helix could contain so many tryptophans, tyrosines, and phenylalanines, yet remain a stable structure. A sheet, perhaps, but not a helix.

We've seen this scoring "bug", before. Is it going to be helpful to give the research lab a designed protein that may unwind before it does any good?

(Sat, 06/09/2012 - 02:56  |  9 comments)
»


Sat, 06/09/2012 - 06:07
#1
 beta_helix 140 3184
beta_helix's picture
User offline. Last seen 5 hours 35 min ago. Offline
Joined: 05/09/2008
Groups: None
Assigned: Anonymous » EvdH

Assigning...

Top
Sat, 06/09/2012 - 06:34
#2
marie_s 140 43
marie_s's picture
User offline. Last seen 1 hour 23 min ago. Offline
Joined: 05/18/2008
Groups: None

sorry I vote down by mistake

Top
Fri, 08/24/2012 - 02:17
#3
 beta_helix 140 3184
beta_helix's picture
User offline. Last seen 5 hours 35 min ago. Offline
Joined: 05/09/2008
Groups: None
Status: Open » Noted

We have tried to resolve this issue and have reposted this puzzle with what we hope is the fix.
Please try it out in devprev and let us know if the problem is still there!

Top
Fri, 08/24/2012 - 06:32
#4
marie_s 140 43
marie_s's picture
User offline. Last seen 1 hour 23 min ago. Offline
Joined: 05/18/2008
Groups: None

the problem seems less pregnant even if my best have 2 TRYP.
As Mark- noticed, the score make leaps. This seems to be leaps of the IE score.

Top
Fri, 08/24/2012 - 17:53
#5
marie_s 140 43
marie_s's picture
User offline. Last seen 1 hour 23 min ago. Offline
Joined: 05/18/2008
Groups: None

the problem is always here
http://fold.it/portal/files/chatimg/irc_33153_1345830773.png

Top
Fri, 08/24/2012 - 19:15
#6
 beta_helix 140 3184
beta_helix's picture
User offline. Last seen 5 hours 35 min ago. Offline
Joined: 05/09/2008
Groups: None
Status: Noted » Ongoing
Assigned: EvdH » tamirh

Thank you marie_s, we'll look into why that solution is still scoring well (as well as the score leaps).

Thanks to everyone that beta-tested this puzzle for us!

Top
Fri, 08/24/2012 - 22:28
#7
Susume 140 15
Susume's picture
User offline. Last seen 9 hours 32 min ago. Offline
Joined: 10/02/2011
Groups: Anthropic Dreams

I see I am late to the party, but I ran a GAB mutate script until I hit 10324 pts, and it had chosen all hydrophobes: WAMWWWYFWW.

Top
Sun, 09/16/2012 - 22:04
#8
marie_s 140 43
marie_s's picture
User offline. Last seen 1 hour 23 min ago. Offline
Joined: 05/18/2008
Groups: None

after many hours of scripts and some manual trying my best have not good scores and many tryps
http://fold.it/portal/files/chatimg/irc_33153_1347832760.png
http://fold.it/portal/files/chatimg/irc_33153_1347832783.png
I find the game very slow and use much memory than usual

Top
Tue, 01/08/2013 - 05:35
#9
BootsMcGraw 14 25
BootsMcGraw's picture
User offline. Last seen 7 hours 53 min ago. Offline
Joined: 12/06/2008
Groups: Contenders
Status: Ongoing » Resolved

With the new Residue IE filter, the abundance of aromatics is ended. But did we go too far? I haven't seen one aromatic in any mutated structure.

Closing this feedback as resolved.

Top
Sitemap

Supported by: UW Center for Game Science, UW Department of Computer Science and Engineering, UW Baker Lab, DARPA, NSF, HHMI, Microsoft, and Adobe