puzzle picture
555: Symmetric Beta Core Design Puzzle 1
Status: Closed

Summary

Name: 555: Symmetric Beta Core Design Puzzle 1
Status: Closed
Created: 05/09/2012
Points: 100
Expired: 05/17/2012 - 08:00
Difficulty: Intermediate
Description: The ...WXCXW... motif adopts a remarkably stable homodimer structure. In fact, it's so tiny, it is difficult to use as a building block for bioengineering; it needs to be larger but retain rigidity. Otherwise anything goes: beta sheets, alpha helix docking, rigid loops, you name it. We've given you 20 extra residues to play with. See what you can do! (Hint: select some residues, set secondary structure to sheet or helix, and hit Rebuild for some quick helices or sheets)
Categories: Design, Overall, Symmetry

Top Groups

RankGroupScorePoints
1Anthropic Dreams9,812100
2L'Alliance Francophone9,80177
3Void Crushers9,71459
4Contenders9,70444
5Go Science9,69333
Show all >

Top Evolvers

RankPlayerGroupScorePoints
1jamiexq 89 197 Anthropic Dreams9,811100
2BitSpawn 89 2536 Anthropic Dreams9,81098
3SimplySue 89 2536 Anthropic Dreams9,80996
4gmn 89 2536 Anthropic Dreams9,80894
5tokens 89 2536 Anthropic Dreams9,80892
Show all >

Top Soloists

RankPlayerGroupScorePoints
1meatexplosion 89 2536 Anthropic Dreams9,812100
2Ch Garnier 89 2536 L'Alliance Francophone9,79398
3marie_s 89 2536  9,72096
4kabubi 89 2536 Void Crushers9,70894
5Bletchley Park 14 49 Contenders9,70492
Show all >


Need this puzzle? Log in to download.  

Comments

Wed, 05/09/2012 - 23:45
#1
 beta_helix 89 2536
beta_helix's picture
User offline. Last seen 2 hours 59 min ago. Offline
Joined: 05/09/2008
Groups: None
More info about this puzzle in the blog:

http://fold.it/portal/node/992627

Feel free to post any questions you might have about this puzzle here, and DrLemming will answer them.

Top
  • 0
Thu, 05/10/2012 - 00:50
#2
jamiexq 89 197
jamiexq's picture
User offline. Last seen 1 day 11 hours ago. Offline
Joined: 07/31/2011
Groups: Anthropic Dreams
Where is the move tool

Is there a move tool with this puzzle?

Top
  • 0
Thu, 05/10/2012 - 05:38
#3
 beta_helix 89 2536
beta_helix's picture
User offline. Last seen 2 hours 59 min ago. Offline
Joined: 05/09/2008
Groups: None
No move tool for this one...

Because we want to preserve the frozen sheets and disulfide bond across the symmetric interface, we had to turn off the move tool and lock residue 7 as well.

Top
  • 0
User login
Download links:
  Windows    OSX    Linux  
Windows
(7/8/10)
OSX
(10.12 or later)
Linux
(64-bit)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Social Media


Search
Only search fold.it
Other Games: Mozak
Recommend Foldit
Topics
Top New Users
Sitemap

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons