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555: Symmetric Beta Core Design Puzzle 1
Status: Closed


Name: 555: Symmetric Beta Core Design Puzzle 1
Status: Closed
Created: 05/09/2012
Points: 100
Expired: 05/17/2012 - 08:00
Difficulty: Intermediate
Description: The ...WXCXW... motif adopts a remarkably stable homodimer structure. In fact, it's so tiny, it is difficult to use as a building block for bioengineering; it needs to be larger but retain rigidity. Otherwise anything goes: beta sheets, alpha helix docking, rigid loops, you name it. We've given you 20 extra residues to play with. See what you can do! (Hint: select some residues, set secondary structure to sheet or helix, and hit Rebuild for some quick helices or sheets)
Categories: Design, Overall, Symmetry

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Joined: 05/09/2008
Groups: None
More info about this puzzle in the blog:


Feel free to post any questions you might have about this puzzle here, and DrLemming will answer them.

jamiexq's picture
User offline. Last seen 23 hours 22 min ago. Offline
Joined: 07/31/2011
Where is the move tool

Is there a move tool with this puzzle?

Joined: 05/09/2008
Groups: None
No move tool for this one...

Because we want to preserve the frozen sheets and disulfide bond across the symmetric interface, we had to turn off the move tool and lock residue 7 as well.

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