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555: Symmetric Beta Core Design Puzzle 1
Status: Closed

Summary

Name: 555: Symmetric Beta Core Design Puzzle 1
Status: Closed
Created: 05/09/2012
Points: 100
Expired: 05/17/2012 - 08:00
Difficulty: Intermediate
Description: The ...WXCXW... motif adopts a remarkably stable homodimer structure. In fact, it's so tiny, it is difficult to use as a building block for bioengineering; it needs to be larger but retain rigidity. Otherwise anything goes: beta sheets, alpha helix docking, rigid loops, you name it. We've given you 20 extra residues to play with. See what you can do! (Hint: select some residues, set secondary structure to sheet or helix, and hit Rebuild for some quick helices or sheets)
Categories: Design, Overall, Symmetry

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RankGroupScorePoints
1Anthropic Dreams9,812100
2L'Alliance Francophone9,80177
3Void Crushers9,71459
4Contenders9,70444
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1jamiexq 46 53 Anthropic Dreams9,811100
2BitSpawn 104 2515 Anthropic Dreams9,81098
3SimplySue 104 2515 Anthropic Dreams9,80996
4gmn 44 64 Anthropic Dreams9,80894
5tokens 32 3 Anthropic Dreams9,80892
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1meatexplosion 104 1307 Anthropic Dreams9,812100
2Ch Garnier 104 2515 L'Alliance Francophone9,79398
3marie_s 104 2515  9,72096
4kabubi 47 39 Void Crushers9,70894
5Bletchley Park 1 28 Contenders9,70492
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Comments

Wed, 05/09/2012 - 23:45
#1
 beta_helix 104 2515
beta_helix's picture
User offline. Last seen 2 weeks 3 days ago. Offline
Joined: 05/09/2008
Groups: None
More info about this puzzle in the blog:

http://fold.it/portal/node/992627

Feel free to post any questions you might have about this puzzle here, and DrLemming will answer them.

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Thu, 05/10/2012 - 00:50
#2
jamiexq 46 53
jamiexq's picture
User offline. Last seen 2 days 10 hours ago. Offline
Joined: 07/31/2011
Groups: Anthropic Dreams
Where is the move tool

Is there a move tool with this puzzle?

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Thu, 05/10/2012 - 05:38
#3
 beta_helix 104 2515
beta_helix's picture
User offline. Last seen 2 weeks 3 days ago. Offline
Joined: 05/09/2008
Groups: None
No move tool for this one...

Because we want to preserve the frozen sheets and disulfide bond across the symmetric interface, we had to turn off the move tool and lock residue 7 as well.

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