puzzle picture
522: Flu Design Puzzle 5
Status: Closed

Groups

RankGroupScorePoints
1Anthropic Dreams11,7500
2Androids11,7040
3Russian team11,6360
4Another Hour Another Point11,6290
5Contenders11,5960
6SETI.Germany11,5890
7Needles and Pins11,5580
8foldeRNA11,5450
9Team Hungary11,5100
10FoldIt@Netherlands11,5060
11Gargleblasters11,4990
12Island Dreams11,4680
13L'Alliance Francophone11,3940
14Void Crushers11,3640
15A97011,3310
16Mmm Helix Fries.11,2330
17Natural Abilities11,1950
18Team Toombs10,9990
19Go Science10,8840
20Team Tornado10,3650


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beta_helix's picture
User offline. Last seen 3 days 9 hours ago. Offline
Joined: 05/09/2008
Groups: None
Here are some sample topologies:



________________________________
More info about this Flu Puzzle:

In this Foldit puzzle the helix is frozen, but you can mutate some of the residues on it.
We want you to build & design both sections on either side of the helix.
To keep the helix from moving, we have cut both those sections on either side of the helix so you can work on them with affecting the helix.
You will notice that both ends have very strong constraints to the either side of the helix.

As discussed in the Scientist Chat (http://fold.it/portal/node/991963) we have also added minimal constraints to keep these two sections in the same general area as the above screenshots.
We have also trimmed as much of the Flu as possible and frozen all its sidechains to speed up Shake and Wiggle.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons