puzzle picture
Beginner Puzzle: Anthrax Lethal Factor Protein
Status: Closed


226raevan 75 1437  9,3628
227Pasanius 75 1437  9,3588
228dropbear 75 1437  9,3547
229pgiles 75 1437  9,3537
230jdretired 75 1437  9,3527
231angel0204 75 1437  9,3517
232gardenpea 75 1437 SETIKAH@KOREA9,3487
233Ujelet 75 1437  9,3467
234sirjeyhmis 75 1437 Geekdo9,3437
235NerdmastaX 75 1437  9,3437
236gcm24 75 1437  9,3437
237wosser1 75 204  9,3427
238pk009 75 1437 SETI.Germany9,3337
239heyubob 75 409  9,3337
240sagkeks 75 1437  9,3337
241liftruck 75 1437  9,3337
242scooper14 75 1437  9,3297
243darioarena 75 1437  9,3286
244doron85 75 1437  9,3266
245lynnai 75 1437 Anthropic Dreams9,3246
246izzytdi 75 1437 Nerdfighters9,3236
247Assaj 75 1437  9,3186
248cramerg 75 1437  9,3146
249rtp101 75 1437  9,3146
250LtUaE42 75 1437  9,3136

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beta_helix's picture
User offline. Last seen 5 hours 4 min ago. Offline
Joined: 05/09/2008
Groups: None
Native guide scores: 9213.678

For those of you interested in knowing the score of the guide, it is at 9213.678. It has not been relaxed or fused at all, so you should be able to improve on that score if you reach the native state. (For example, fusing the native 3 times gives a score of 9415.568)

If you are new to Foldit, here are detailed instructions to get you started:

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons