puzzle picture
Beginner Puzzle: Anthrax Lethal Factor Protein
Status: Closed

Soloists

RankPlayerGroupScorePoints
201Sergey2002 46 1458  9,4269
202bubbery 46 1458  9,4229
203Jeffaschn 46 1458  9,4209
204georg137 18 35  9,4209
205Lollie 46 1458 Richard Dawkins Foundation9,4189
206Merf 46 73  9,4169
207Ribo-soma 46 1458 Hun-Magyar Csapat9,4159
208guineapig 23 15  9,4139
209Simas171 46 1458  9,4139
210oaks 46 1458  9,4109
211biomisha 46 1458  9,4099
212DrMistry 46 1458  9,4099
213spirogyra 46 1458  9,4069
214lbk101 46 1458  9,4048
215FreeFolder 46 1458  9,3968
216ourtown 46 1458  9,3918
217WBarme1234 46 20  9,3878
218pheobe32821 46 1458  9,3788
219MichaelJeong 46 1458  9,3768
220shelley 46 1458  9,3748
221Bautho 46 118  9,3698
222multaq 46 550 L'Alliance Francophone9,3668
223hada 46 416  9,3668
224wlof 46 1458  9,3648
225martinf 46 1458  9,3638


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beta_helix's picture
User offline. Last seen 4 days 1 hour ago. Offline
Joined: 05/09/2008
Groups: None
Native guide scores: 9213.678

For those of you interested in knowing the score of the guide, it is at 9213.678. It has not been relaxed or fused at all, so you should be able to improve on that score if you reach the native state. (For example, fusing the native 3 times gives a score of 9415.568)
_______________________________________________________________

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons