puzzle picture
Beginner Puzzle: Anthrax Lethal Factor Protein
Status: Closed

Soloists

RankPlayerGroupScorePoints
176ncm25_OLD 46 1458  9,48812
177kdieber 46 1458  9,48412
178GeraudSansom 46 1458  9,48012
179jezsissek 46 1458  9,47712
180GreekCivilization 46 1458  9,47311
181bblattmann 46 1458  9,47011
182t_backdahl 46 1458  9,46911
183halvebounty 46 1458  9,46811
184smhirt 46 1458  9,46611
185alex.wveit 46 1458  9,46411
186snakeguy 46 1458  9,46111
187Jpnezboi 46 1458  9,46111
188bloodyviking 46 1458  9,46011
189M_Andela 46 1458  9,45911
190Nonsense 46 1458  9,45910
191Brockwell 46 1458  9,45610
192itskimo 46 1458 foldeRNA9,45310
193Tlaloc 46 1458 Mojo Risin'9,45210
194Bloodfly 46 1458  9,45110
195scify 46 1458  9,44710
196Delusionsofholbert 46 1458  9,43610
197KFN 46 1458  9,43210
198aendgraend 46 1458 SETI.Germany9,43210
199Chopsticks94 46 1458 Androids9,43010
200mens-rea 46 1458  9,42910


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beta_helix's picture
User offline. Last seen 5 days 5 min ago. Offline
Joined: 05/09/2008
Groups: None
Native guide scores: 9213.678

For those of you interested in knowing the score of the guide, it is at 9213.678. It has not been relaxed or fused at all, so you should be able to improve on that score if you reach the native state. (For example, fusing the native 3 times gives a score of 9415.568)
_______________________________________________________________

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons