puzzle picture
Beginner Puzzle: Anthrax Lethal Factor Protein
Status: Closed


251Uganalandia 75 1437 9,3126
252albertoveneto 75 1437  9,3126
253sjoerdouwe 75 1437  9,3096
254ch00215 75 1437  9,3046
255michelw 75 1437  9,3046
256trabis 75 1437  9,3036
257sbea3 75 1437  9,3026
258Sadler 75 1437 Russian team9,3006
259lukykl 75 1437  9,2996
260crawlee34225 75 1437  9,2936
261chessey 75 1437  9,2925
262foldzapr 75 1437  9,2915
263khopper 75 1437  9,2905
264IndubitablyThomas 75 1437  9,2875
265frostschutz 75 107  9,2865
266capnsparrow 75 1437  9,2845
267dbuske 75 1437 9,2845
268Wiredguy 75 1437  9,2835
269XXWhiteKnightXX 75 1437  9,2835
270Squirrely 75 1437  9,2815
271amuebx 75 1437  9,2815
272crpainter 75 1437  9,2765
273salish99 75 1437 Geekdo9,2755
274Larry Pierce 75 1437  9,2725
275Bartosz Gr... 75 1437 Go Science9,2695

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beta_helix's picture
User offline. Last seen 3 hours 57 min ago. Offline
Joined: 05/09/2008
Groups: None
Native guide scores: 9213.678

For those of you interested in knowing the score of the guide, it is at 9213.678. It has not been relaxed or fused at all, so you should be able to improve on that score if you reach the native state. (For example, fusing the native 3 times gives a score of 9415.568)

If you are new to Foldit, here are detailed instructions to get you started:

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons