puzzle picture
Beginner Puzzle: Anthrax Lethal Factor Protein
Status: Closed

Groups

RankGroupScorePoints
1Anthropic Dreams10,23050
2Contenders10,20944
3L'Alliance Francophone10,17838
4Void Crushers10,16233
5Go Science10,15429
6Androids10,12225
7Team Tornado10,10521
8A97010,06718
9foldeRNA10,04016
10Totems10,02713
11Gargleblasters10,00911
12FoldIt@Netherlands10,00610
13Team Hungary9,9518
14SETI.Germany9,8807
15Russian team9,8806
16Richard Dawkins Foundation9,8605
17Nerdfighters9,8444
18Biology-4th9,7883
19Natural Abilities9,7723
20Island Dreams9,7702
21Freedom Folders9,7502
22Needles and Pins9,7472
23xkcd9,7011
24Piratenpartei Deutschland9,6921
25CHNO Junkies9,6601


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Comments

beta_helix's picture
User offline. Last seen 1 hour 58 min ago. Offline
Joined: 05/09/2008
Groups: None
Native guide scores: 9213.678

For those of you interested in knowing the score of the guide, it is at 9213.678. It has not been relaxed or fused at all, so you should be able to improve on that score if you reach the native state. (For example, fusing the native 3 times gives a score of 9415.568)
_______________________________________________________________

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons