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460: Quest to the SOLVED Monkey Virus Protein
Status: Closed

Summary

Name: 460: Quest to the SOLVED Monkey Virus Protein
Status: Closed
Created: 09/23/2011
Points: 100
Expired: 10/03/2011 - 23:00
Difficulty: Intermediate
Description: The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days!
Categories: Overall, Prediction

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RankGroupScorePoints
1Void Crushers10,577100
2Anthropic Dreams10,47387
3foldeRNA10,46975
4Contenders10,46764
5Androids10,46555

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Comments

beta_helix's picture
User offline. Last seen 19 weeks 5 days ago. Offline
Joined: 05/09/2008
Groups: None
This was the famous Unsolved Monkey Virus Protein

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.

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