puzzle picture
452: De-novo Freestyle 13
Status: Closed

Summary

Name: 452: De-novo Freestyle 13
Status: Closed
Created: 08/29/2011
Points: 100
Expired: 09/07/2011 - 11:00
Difficulty: Advanced
Description: We are giving you this currently unsolved protein as an extended chain. Use all your beta-sheet forming skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.
Categories: Overall, Prediction

Top Groups

RankGroupScorePoints
1Void Crushers11,022100
2Contenders10,87272
3foldeRNA10,83750
4L'Alliance Francophone10,66334
5Anthropic Dreams10,65323

Top Evolvers

Top Soloists

RankPlayerGroupScorePoints
1steveB 79 1423 Void Crushers10,992100
2aap 79 1423  10,91697
3mimi 79 1423 Contenders10,85593
4wudoo 79 347 foldeRNA10,81989
5deus911 79 1423 foldeRNA10,77486


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Comments

beta_helix's picture
User offline. Last seen 1 day 3 hours ago. Offline
Joined: 05/09/2008
Groups: None
Please try to use these secondary structure predictions:

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 87 is highly predicted to be part of a sheet. However, the Serine at residue 81 has an equal probability of being anything.

_________________________________________________________________

Because this is a long protein, we are giving you 1 extra day to work on it.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons