puzzle picture
434: De-novo Freestyle 9
Status: Closed


Name: 434: De-novo Freestyle 9
Status: Closed
Created: 06/27/2011
Points: 100
Expired: 07/05/2011 - 07:00
Difficulty: Advanced
Description: We are giving you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.
Categories: Overall, Prediction

Top Groups

2Void Crushers10,86079
4Anthropic Dreams10,81548
5Go Science10,65837

Top Evolvers

Top Soloists

1wld333 173 16927 foldeRNA10,959100
2marie_s 173 16927  10,87998
3spmm 106 33 Void Crushers10,86095
4wudoo 89 97 foldeRNA10,84892
5Mark- 173 16927 Contenders10,81990

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Joined: 05/09/2008
Groups: None
Please try to use these secondary structure predictions:

These secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 18 is highly predicted to be part of a sheet. However, the Leucines at residue 122-123 are highly predicted to be in a helix.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons