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430: Easy Mini Freestyle Puzzle 1b
Status: Closed


Name: 430: Easy Mini Freestyle Puzzle 1b
Status: Closed
Created: 06/13/2011
Points: 75
Expired: 06/18/2011 - 01:00
Difficulty: Beginner
Description: We are giving you this currently unsolved short protein as an extended chain one last time. This time we are providing you with secondary structure predictions (available in the puzzle comments) that are pre-loaded in the puzzle. This puzzle will be worth 75 global points.
Categories: Overall, Prediction

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beta_helix's picture
User offline. Last seen 58 min 40 sec ago. Offline
Joined: 05/09/2008
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Please try to use these secondary structure predictions:

This time we are providing you with secondary structure predictions (below) but you are unable to load previous solutions because we want to see how different your trajectories are when given secondary structure predictions.

As requested in the feedback, http://fold.it/portal/node/989298 these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 28 is highly predicted to be part of a helix. However, the Serine at residue 39 is equally predicted to be anything.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons