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423: H2N2 Flu Design Puzzle 1
Status: Closed


Name: 423: H2N2 Flu Design Puzzle 1
Status: Closed
Created: 05/26/2011
Points: 0
Expired: 05/29/2011 - 06:03
Difficulty: Intermediate
Description: This puzzle had an error in it and has been reposted as Puzzle 425, sorry for the trouble with this.
Categories: Design, Overall

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Joined: 05/09/2008
Groups: None
This puzzle requires the latest update

In order to play this exciting puzzle (worth 150 global points) make sure to download the latest update (it should download automatically when launching Foldit).

Joined: 08/06/2010
Groups: Contenders
Which half of this is the virus?

If I understand our challenge correctly, we are intended to form a binding pocket between some known substance and H2N2. It makes very little sense to me to have both compounds mutatable. One is the virus fragment, the other is our detector molecule (or inhibitor or whatever... ) That should have been the only part of this puzzle we could mutate, right? Which half is which?

I don't see how mutating the target protein is useful to solve the science portion of this challenge. I mean we can't actually mutate the virus to make it more sticky to the other molecule in the wild, can we?


Joined: 05/09/2008
Groups: None
Thank you for catching that mistake!

We have reposted this puzzle correctly: http://fold.it/portal/node/989783

Thank you again for bringing this up and we are very sorry for this error.

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