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404: De-novo Freestyle 4
Status: Closed
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Summary
| Name: |
404: De-novo Freestyle 4 |
| Status: |
Closed |
| Created: |
03/09/2011 |
| Points: |
100 |
| Difficulty: |
Advanced |
| Description: |
This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well. |
| Categories: | Overall, Prediction |
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| pauldunn 28 22 | Beginner Puzzle...xin | 9,913 | | fold.like.a.c...ion 139 1689 | Beginner Puzzle...xin | 9,388 | | yreeen 139 4570 | Beginner Puzzle...xin | 9,580 | | etFolly 139 6857 | 716 (<15): Two ...ant | 8,529 | | Bjro 139 1764 | 716 (<150): Two...ant | 8,712 | | marie_s 139 39 | 716: Two chains...ant | 8,912 | | hansvandenhof 20 9 | 714: 5-year-ann...012 | 11,122 | | Mark- 139 94 | 713: 5-year-ann...011 | 13,310 | | markm457 2 2 | Beginner Puzzle...yme | 11,388 | | zeroblue 139 6857 | Beginner Puzzle...yme | 11,148 | | zeroblue 139 6857 | Beginner Puzzle...yme | 11,013 |
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| pauldunn 28 22 | Beginner Puzzle...xin | 9,913 | | fold.like.a.c...ion 139 1689 | Beginner Puzzle...xin | 9,388 | | yreeen 139 4570 | Beginner Puzzle...xin | 9,580 | | etFolly 139 6857 | 716 (<15): Two ...ant | 8,529 | | Bjro 139 1764 | 716 (<150): Two...ant | 8,712 | | marie_s 139 39 | 716: Two chains...ant | 8,912 | | hansvandenhof 20 9 | 714: 5-year-ann...012 | 11,122 | | Mark- 139 94 | 713: 5-year-ann...011 | 13,310 | | markm457 2 2 | Beginner Puzzle...yme | 11,388 | | zeroblue 139 6857 | Beginner Puzzle...yme | 11,148 | | zeroblue 139 6857 | Beginner Puzzle...yme | 11,013 |
| Go Science | Beginner Puzzle...xin | 9,913 | | Anthropic Dreams | Beginner Puzzle...xin | 8,938 | | NETD | 716 (<15): Two ...ant | 8,450 | | NETD | 716 (<150): Two...ant | 8,407 | | Anthropic Dreams | 716: Two chains...ant | 8,879 | | Anthropic Dreams | 714: 5-year-ann...012 | 11,140 | | Contenders | 713: 5-year-ann...011 | 13,310 | | Anthropic Dreams | Beginner Puzzle...yme | 11,388 | | Gargleblasters | Beginner Puzzle...yme | 11,080 | | NWFSC CHS | Beginner Puzzle...yme | 10,806 |
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As requested in the feedback, http://fold.it/portal/node/989298, these secondary structure predictions have been pre-loaded into this freestyle puzzle.
Here is the sequence logo predicted by the SAM server.
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the amino acid Isoleucine at residue 29 is highly predicted to be part of a helix. However, the Leucine at residue 97 is predicted to have an equal probability of being anything.