puzzle picture

288: Mini-CASP 22 - Trimmed Sequence

Status: Closed

Soloists

Rank	Player	Group	Score	Points
1	aap 174 13410	Richard Dawkins Foundation	11,083	100
2	CharlieFortsCon... 31 68	Contenders	10,904	95
3	mimi 4 12	Contenders	10,900	90
4	Mark- 80 59	Contenders	10,870	85
5	HillObserver 174 13410	Void Crushers	10,820	80
6	keypad5 174 13410	Richard Dawkins Foundation	10,770	75
7	drjr 126 108	Anthropic Dreams	10,519	71
8	BootsMcGraw 15 15	Contenders	10,501	67
9	TheGUmmer 58 33	Void Crushers	10,471	63
10	vakobo 174 13410	Russian team	10,456	60
11	vertex 142 148	Richard Dawkins Foundation	10,442	56
12	weitzen 174 138		10,403	53
13	mat747 69 34	Void Crushers	10,388	50
14	Savas 174 352		10,298	47
15	Susanne 57 111	SETI.Germany	10,291	44
16	Pletsch 174 8067	Anthropic Dreams	10,241	41
17	auntdeen 43 18		10,232	39
18	Brick 174 13410	GreatScience	10,212	36
19	Jim Fraser 174 103	Contenders	10,193	34
20	Mr_Jolty 174 185	Natural Abilities	10,157	32
21	Renton 105 126	Anthropic Dreams	10,154	30
22	aendgraend 60 216	SETI.Germany	10,150	28
23	Ozmandias 174 13410		10,145	26
24	SKSbell 174 106		10,110	24
25	steveB 121 20	Void Crushers	10,108	23

Comments

Wed, 04/21/2010 - 05:49

#1

beta_helix 174 3221

beta_helix's picture

Online

Joined: 05/09/2008

Groups: None

Disorder at the N-terminus?

As you noticed in puzzle 284: Mini-CASP 22 - Single Template, the first 23 residues did not align to the template in the starting alignments.
So we ran this sequence through the Disorder Prediction Servers (using metaPrDOS: protein disorder meta-prediciton server) and here are the results:

You can see that all but one of the disorder prediction servers believe that the N-terminus is indeed disordered, so this is why we have trimmed the first 13 residues.

Get Started: Download


Windows (XP/Vista/7)	OSX (Intel 10.4 or later)	Linux (64-bit)

Recommend Foldit


	User login Username: * Password: * Create new account Request new password Sign in using Facebook

Soloists

Evolvers

Groups

Topics

Player	Puzzle	Score
AsDawnBreaks 174 295	563: Server mod...668	9,834
spdenne 16 28	562: Quick Symm...zle	14,114
meatexplosion 39 7	559: CASP10 Tar...673	10,069
torobi20 174 1346	Beginner Puzzle...ein	9,916
Olyndar 102 182	Beginner Puzzle...ein	10,054
randomlil 52 32	Beginner Puzzle...ein	10,093
Mark- 80 59	561: CASP10 Tar...678	11,500


	Facebook Fan Page


	Top New Users gitwut tamirh zlacker dedfed AsDawnBreaks

Supported by: UW Center for Game Science, UW Department of Computer Science and Engineering, UW Baker Lab, DARPA, NSF, HHMI, Microsoft, and Adobe