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286: Mini-CASP 20 - Better Alignments?
Status: Closed
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Soloists
| 1 | Mark- 80 59 | Contenders | 10,894 | 100 | | 2 | aap 174 13410 | Richard Dawkins Foundation | 10,846 | 97 | | 3 | Steven Pletsch 162 116 | Another Hour Another Point | 10,740 | 93 | | 4 | HillObserver 174 13410 | Void Crushers | 10,704 | 90 | | 5 | keypad5 174 13410 | Richard Dawkins Foundation | 10,667 | 87 | | 6 | BootsMcGraw 15 15 | Contenders | 10,664 | 83 | | 7 | spvincent 48 57 | Another Hour Another Point | 10,656 | 80 | | 8 | vertex 142 148 | Richard Dawkins Foundation | 10,592 | 77 | | 9 | mimi 4 12 | Contenders | 10,579 | 74 | | 10 | TheGUmmer 58 33 | Void Crushers | 10,512 | 71 | | 11 | Coskun 174 502 | Richard Dawkins Foundation | 10,506 | 69 | | 12 | CharlieFortsCon... 31 68 | Contenders | 10,497 | 66 | | 13 | Cartoon Villain 174 13410 | | 10,494 | 64 | | 14 | katling 174 879 | | 10,482 | 61 | | 15 | SKSbell 174 106 | | 10,453 | 59 | | 16 | aendgraend 60 216 | SETI.Germany | 10,405 | 56 | | 17 | vakobo 174 13410 | Russian team | 10,404 | 54 | | 18 | JPC119 174 13410 | | 10,379 | 52 | | 19 | Brick 174 13410 | GreatScience | 10,360 | 50 | | 20 | Dolichwier 76 559 | | 10,345 | 48 | | 21 | Bletchley Park 6 3 | Contenders | 10,341 | 46 | | 22 | mama kurt 174 13410 | Mad Lab | 10,313 | 44 | | 23 | tallguy-13088 174 75 | | 10,251 | 42 | | 24 | drjr 126 108 | | 10,243 | 41 | | 25 | Madde 81 26 | Void Crushers | 10,239 | 39 |
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Many of you noticed (http://fold.it/portal/node/987562) that in puzzle '283: Mini-CASP 20 - Alignments' there were stretched bonds after threading.
Normally, when you thread and a gap needs to be resolved, Foldit fixes this by shrinking the loop.
The problem in this case was that the solved structures for these templates actually had these stretched bonds!!!
Attached is a screenshot of one of the templates: 1n8z (http://www.rcsb.org/pdb/explore/images.do?structureId=1N8Z).
The gap in yellow at the top is in the solved structure. You would think that this is just missing density (that there are a few residues in between there that were disordered or couldn't be solved) but no: that gap is from Leucine 101 to Serine 102.
Sadly, there is nothing we can do about this sort of thing (other than give you what are hopefully better templates) and it might be the case during CASP 9 that the 'best' templates have these kinds of problems!