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286: Mini-CASP 20 - Better Alignments?
Status: Closed
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All-Hands Players
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| 1 | vakobo 174 13410 | Russian team | 10,974 | 100 | | 2 | steveB 121 20 | Void Crushers | 10,973 | 97 | | 3 | Mark- 80 59 | Contenders | 10,969 | 93 | | 4 | Dolichwier 76 559 | Void Crushers | 10,969 | 90 | | 5 | Grom 100 113 | Russian team | 10,969 | 87 | | 6 | Madde 81 26 | Void Crushers | 10,969 | 83 | | 7 | marie_s 174 46 | | 10,968 | 80 | | 8 | g_b 174 13410 | | 10,966 | 77 | | 9 | srssmith92 174 13410 | ExPitneyFolders | 10,961 | 74 | | 10 | Savas 174 352 | | 10,961 | 71 | | 11 | CharlieFortsCon... 31 68 | Contenders | 10,961 | 69 | | 12 | Coskun 174 502 | Richard Dawkins Foundation | 10,960 | 66 | | 13 | chh9513136 174 13410 | | 10,960 | 64 | | 14 | Bletchley Park 6 3 | Contenders | 10,960 | 61 | | 15 | drbh 174 13410 | Richard Dawkins Foundation | 10,958 | 59 | | 16 | crusaderv83 174 13410 | | 10,956 | 56 | | 17 | dimension9 174 13410 | Anthropic Dreams | 10,951 | 54 | | 18 | Game Cat 174 13410 | | 10,951 | 52 | | 19 | spvincent 48 57 | Another Hour Another Point | 10,947 | 50 | | 20 | TheGUmmer 58 33 | Void Crushers | 10,944 | 48 | | 21 | maxwell_thethird 174 13410 | Richard Dawkins Foundation | 10,941 | 46 | | 22 | Renton 105 126 | Anthropic Dreams | 10,940 | 44 | | 23 | keypad5 174 13410 | Richard Dawkins Foundation | 10,929 | 42 | | 24 | mimi 4 12 | Contenders | 10,925 | 41 | | 25 | setiman 174 13410 | Richard Dawkins Foundation | 10,925 | 39 | Comments
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Many of you noticed (http://fold.it/portal/node/987562) that in puzzle '283: Mini-CASP 20 - Alignments' there were stretched bonds after threading.
Normally, when you thread and a gap needs to be resolved, Foldit fixes this by shrinking the loop.
The problem in this case was that the solved structures for these templates actually had these stretched bonds!!!
Attached is a screenshot of one of the templates: 1n8z (http://www.rcsb.org/pdb/explore/images.do?structureId=1N8Z).
The gap in yellow at the top is in the solved structure. You would think that this is just missing density (that there are a few residues in between there that were disordered or couldn't be solved) but no: that gap is from Leucine 101 to Serine 102.
Sadly, there is nothing we can do about this sort of thing (other than give you what are hopefully better templates) and it might be the case during CASP 9 that the 'best' templates have these kinds of problems!