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2015: Symmetric D2 Tetramer Design: H-bond Networks
Status: Closed
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Groups
| 1 | Contenders | 28,493 | 100 |
| 2 | Go Science | 27,607 | 60 |
| 3 | Anthropic Dreams | 27,191 | 33 |
| 4 | Beta Folders | 26,810 | 17 |
| 5 | Gargleblasters | 26,087 | 8 |
| 6 | Marvin's bunch | 24,929 | 4 |
| 7 | Void Crushers | 24,096 | 2 |
| 8 | L'Alliance Francophone | 23,884 | 1 |
| 9 | Australia | 23,059 | 1 |
| 10 | BOINC@Poland | 22,468 | 1 |
| 11 | SETI.Germany | 15,125 | 1 |
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Comments
Buried Unsats (max +500)
Penalizes polar atoms that cannot make hydrogen bonds, -200 points per atom (not including symmetric copies).
Core Existence: Monomer (max +2000)
Ensures that at least 20 residues are buried in the core of the monomer unit.
Core: Complex (max +0)
Awards no bonuses or penalties. Click Show to see which residues count as "Core" for the H-bond Network objective.
Interaction Energy (max +500)
Monitors that all large PHE, TYR, and TRP residues are scoring well.
H-bond Network (max +2400)
Rewards networks that comprise at least 2 H-bonds involving core residues.
Between 1 and 12 H-bonds should cross the interface between symmetric units.
Networks must be at least 75% satisfied (i.e. 75% of all bondable atoms in a network must make a H-bond).
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.