20201223-e20c1e0f15-win_x86 bad loop shows ONE residu in a helix

Case number:671071-2011112
Topic:Game: Other
Opened by:Bletchley Park
Opened on:Sunday, January 24, 2021 - 09:34
Last modified:Tuesday, March 2, 2021 - 03:28

20201223-e20c1e0f15-win_x86 solution shared with scientists: 'faulty_filter'

When checking for bad loops, ONE residu in the middle of a longer helix is highlighted.
Working on the helix segment can get rid of the 'bad loop' designation but it seems odd to me that a helix section is identified as a loop.


(Sun, 01/24/2021 - 09:34  |  4 comments)

Joined: 12/06/2008
Groups: Contenders

I have the same issue on puzzle 1951. One of the four residues in my loop (203-206) is marked as a bad loop, while the rest of the loop shows to be okay. Engaging the "Auto Structures" function changes 203-205 to an extension of helix 186-202.

How can one residue residing between two helices be marked a non-ideal loop?

My structure: https://ibb.co/nbHryJs
Auto Structure: https://ibb.co/bm8NPzC

Joined: 12/06/2008
Groups: Contenders

Uploaded to scientists as "1-residue-bad-loop".

Joined: 12/06/2008
Groups: Contenders

I am still seeing this in design puzzles. I have found there is no way to remove this penalty, no matter how many hundred times I remix/rebuild that section of my protein.

Joined: 12/06/2008
Groups: Contenders

Here is the latest 1-residue bad loop, this time at the very end residue of 1960:


I'll upload this solution to the scientists, if y'all want it.


Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons